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Celiac Disease Testing

Aim: The most common blood test that could confirm if a person has Celiac Disease is called tTG-IgA test or Tissue Transglutaminase Antibodies. Other tests include Anti-TTG Antibodies, IGg, Anti-DGP Antibodies, IGa and Anti-DGP Antibodies IGg. These test will produce a positive result for 98% of patients with Celiac Disease and on a gluten-containing diet. This is also known as a Sensitivity Test. This test can provide a false positive result for patients with autoimmune disorders such as Diabetes type 1, Chronic Liver Disease, Psoriasis, Hashimoto’s Thyroiditis, Rheumatoid Arthritis and Heart Failure. However, there are certain tests to double-check or confirm potential false positive and false negative results.

Equipment required: 3cc to 5cc syringe, cotton balls, blood test tube with name, age and gender of the patient, tourniquet, alcohol and test tube holder.

Procedure: Before the procedure, the medical technologist will check your name and other personal details. A tourniquet will be wrapped near the vein where blood will be extracted. The area from where the blood will be drawn will be cleansed using a cotton ball with alcohol to ensure cleanliness of the surrounding area. The medical technologist will draw blood from the vein with using a syringe, and the blood colelcted in a tube for testing.

Results: A person who has been diagnosed with Celiac Disease and has been already following a gluten-free diet, must have low levels of autoantibody. However, if the symptoms and the result still present a high level of antibodies, then the patient might have one of the rarest forms of Celiac Disease that is unresponsive to dietary restrictions. A Biopsy is recommended to all positive and indeterminate results. A biopsy can further screen and confirm for the presence of Celiac Disease.

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